Peter Parker is going through a major identity crisis. Burned out from being Spider-Man, he decides to shelve his superhero alter ego, which leaves the city suffering in the wake of carnage left by the evil Doc Ock. In the meantime, Parker still can't act on his feelings for Mary Jane Watson, a girl he's loved since childhood. A certain anger begins to brew in his best friend Harry Osborn as well...
Tobey Maguire Kirsten Dunst James Franco Alfred Molina Rosemary Harris J.K. Simmons Donna Murphy Daniel Gillies Dylan Baker Bill Nunn Vanessa Ferlito Aasif Mandvi Willem Dafoe Cliff Robertson Ted Raimi Elizabeth Banks Bruce Campbell Gregg Edelman Elya Baskin Mageina Tovah Daniel Dae Kim Hal Sparks Joel McHale Stan Lee Kelly Connell Brent Briscoe Emily Deschanel Scott Spiegel Andy Bale Christine Estabrook Molly Cheek John Paxton Joy Bryant Joanne Baron Peter McRobbie Timothy Jerome Taylor Gilbert Louis Lombardi Elyse Dinh Phil LaMarr
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